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Syllabus 2022-23 - 76713007 - Biotechnological Methods of Disease Diagnosis (Biotecnología diagnóstica)

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  • Level 1: Tutorial support sessions, materials and exams in this language
  • Level 2: Tutorial support sessions, materials, exams and seminars in this language
  • Level 3: Tutorial support sessions, materials, exams, seminars and regular lectures in this language
DEGREE: Máster Univ. en Biotecnología y biomedicina (76713007)
FACULTY: Centro de Estudios de Postgrado
DEGREE: Doble Máster en Biotecnología y Biomedicina y MFPES (Profesorado) (77913007)
FACULTY: Centro de Estudios de Postgrado
ACADEMIC YEAR: 2022-23
COURSE: Biotechnological Methods of Disease Diagnosis
SYLLABUS
1. COURSE BASIC INFORMATION
NAME: Biotechnological Methods of Disease Diagnosis
CODE: 76713007 (*) ACADEMIC YEAR: 2022-23
LANGUAGE: English LEVEL: 1
ECTS CREDITS: 3.0 YEAR: 1 SEMESTER: SC
2. LECTURER BASIC INFORMATION
NAME: CARUZ ARCOS, ANTONIO JOSÉ
DEPARTMENT: U103 - BIOLOGÍA EXPERIMENTAL
FIELD OF STUDY: 420 - GENÉTICA
OFFICE NO.: B3 - 344 E-MAIL: caruz@ujaen.es P: 953212706
WEBSITE: www.ujaen.es/investiga/inmunoge
ORCID: https://orcid.org/0000-0002-5788-7840
LANGUAGE: - LEVEL: 1
3. CONTENT DESCRIPTION

1. Cytology and molecular histology in clinical diagnosis:
1.1. Immunohistochemistry (monoclonal and polyclonal antibodies)
1.2. in situ hybridization
2. Flow cytometry

3. Biosensors
4. Molecular biology in clinical diagnosis I:
4.1. Quantification of gene expression by real-time PCR and its
applications
4.2. Multiple real-time PCR techniques for diagnosis
5. Molecular biology in clinical diagnosis II:
5.1. Advanced massive DNA sequencing techniques
5.2. Real-time PCR SNP genotyping techniques
5.3. Massive genotyping techniques (veracode, Illumina, etc.)
5.4. Microsatellite and copy number variation genotyping techniques
5.5. Haplotype calculation and genetic risk quantification
5.6. Expression microarrays, CGH and microRNAs in clinical
diagnosis, application to the characterization of
tumors and endometrial receptivity.
6. Paternity analysis and forensic genetics
7. Genetic counseling and calculation of probabilities
8. Diagnostic reagent production biotechnology
9. Regulations, legislation and patents in molecular diagnostics

Integration of sustainable development goals. The contents of this
subject connect with sustainable development goal No. 3 Guarantee a
healthy life and promote well-being for all at all ages and No. 4
Guarantee inclusive, equitable and quality education and promote
learning opportunities throughout life for everyone.

4. COURSE DESCRIPTION AND TEACHING METHODOLOGY

Master class sessions in a large group in which the essential
theoretical contents will be presented. Four external invited
speakers, experts in diagnostic biotechnology and linked to the
business and hospital world (biosensors, microarrays, massive
sequencing and clinical genetics). Practical classes in which
different immunohistochemical and genetic diagnosis techniques will
be carried out, as well as the analysis of massive genotyping data.
Student seminars and discussion sessions on real cases.

Students with special educational needs should contact the Student Attention Service (Servicio de Atención y Ayudas al Estudiante) in order to receive the appropriate academic support

5. ASSESSMENT METHODOLOGY

Ordinary evaluation: To evaluate attendance at both
theoretical and practical classes, a roll call will be taken in
each session. The proactivity and participation of the students in
all the proposed activities will be evaluated, being especially
significant the capacity for debate and argumentation in the
discussion after the seminars. As well as in the theoretical
questions and issues raised by the teaching staff throughout the
theoretical and practical classes. Each student must submit a
report of the practices carried out, a work consisting of the
review of a topic or a scientific article, as well as giving a
seminar. Extraordinary evaluation: exam of the theoretical and
practical contents and recovery work or seminar.

6. BOOKLIST
MAIN BOOKLIST:
  • Molecular cloning : a laboratory manual. Edition: 4th ed. Author: Green, Michael R. Michael Richard, 1954-. Publisher: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, 2012  (Library)
ADDITIONAL BOOKLIST:
  • Apoptosis, Cell Signaling, and Human Diseases [Recurso electrónico] : Molecular Mechanisms. Edition: -. Author: Srivastava, Rakesh. Publisher: Totowa, NJ : Humana Press Inc., 2007.  (Library)
  • In situ detection of DNA damage: methods and protocols. Edition: -. Author: -. Publisher: Totowa: Humana Press, cop. 2002  (Library)
  • Flow Cytometry [Recurso electrónico] : Principles and Applications. Edition: -. Author: Macey, Marion G.. Publisher: Totowa, NJ : Humana Press Inc., 2007.  (Library)
8. VIRTUAL / CLASSROOM TEACHING SCENARIO

La metodología docente y sistema de evaluación pra PATIE será la misma que se ha especificado en el escenario presencial

9. VIRTUAL TEACHING SCENARIO

La metodología docene y evaluación para PATIE, será la misma que la aplicada en el escenario presencial

DATA PROTECTION CLAUSE (on line exams)

Institution in charge of data processing: Universidad de Jaén, Campus Las Lagunillas, s/n, 23071 Jaén

Data Protection Delegate: dpo@ujaen.es

Purpose: In accordance with the Universities Law and other national and regional regulations in force, carrying out exams and assessment tests corresponding to the courses students are registered in. In order to avoid frauds while sitting the exam, the exam will be answered using a videoconference system, being able the academic staff of the University of Jaén to compare and contrast the image of the person who is answering the exam with the student's photographic files. Likewise, in order to provide the exam with evidential content for revisions or claims, in accordance with current regulation frameworks, the exam will be recorded and stored.

Legitimacy: compliance with legal obligations (Universities Law) and other national and regional regulations currently in force.

Addressees: service providers who are the owners of the platforms where the exams are carried out and with whom the University of Jaén has signed the corresponding data access contracts.

Storage periods: those established in current in force regulations. In the specific case of exam videoconference recordings, not before the examination records and transcripts are closed or the exam can still be reviewed or challenged.

Rights: you can exercise your right of access, amendment, cancellation, opposition, suppression, limitation and portability by sending a letter to the postal or electronic address indicated above. In the event that you consider that your rights have been violated, you may submit a complaint to the Andalusian Council for Transparency and Data Protection www.ctpdandalucia.es

CLASS RECORDING CLAUSE PERSONAL DATA PROTECTION

Person in charge: Universidad de Jaén, Paraje Las Lagunillas, s/n; Tel.953 212121; www.ujaen.es

Data protection delegate (DPO): TELEFÓNICA, S.A.U. ; Email: dpo@ujaen.es

Procedure aim: To manage proper recordings of teaching sessions with the aim of facilitating learning process under a multimodal and/or online teaching

Period for record storage: Images will be kept during legal term according to regulations in force

Legitimacy: Data will be managed according to legal regulations (Organic Law 6/2001, December 21, on Universities) and given consent provided by selecting corresponding box in legal admission documents

Data recipients (transfers or assignments): Any person allowed to get access to every teaching modality

Rights: You may exercise your rights of access, rectification, cancellation, portability, limitation of processing, deletion or, where appropriate, opposition. To exercise these rights, you must submit a written request to the Information, Registration and Electronic Administration Service of the University of Jaen at the address above, or by e-mail to the address above. You must specify which of these rights you are requesting to be satisfied and, at the same time, you must attach a photocopy of your ID card or equivalent identification document. In case you act through a representative, legal or voluntary, you must also provide a document that proves this representation and identification. Likewise, if you consider that your right to personal data protection has been violated, you may file a complaint with the Andalusian Data Protection and Transparency Council www.ctpdandalucia.es