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Syllabus 2022-23 - 10213004 - Metabolic and Molecular Biochemistry (Bioquímica metabólica y molecular)
- Level 1: Tutorial support sessions, materials and exams in this language
- Level 2: Tutorial support sessions, materials, exams and seminars in this language
- Level 3: Tutorial support sessions, materials, exams, seminars and regular lectures in this language
| DEGREE: | Grado en Biología |
| FACULTY: | FACULTY OF EXPERIMENTAL SCIENCES |
| ACADEMIC YEAR: | 2022-23 |
| COURSE: | Metabolic and Molecular Biochemistry |
| NAME: Metabolic and Molecular Biochemistry | |||||
| CODE: 10213004 | ACADEMIC YEAR: 2022-23 | ||||
| LANGUAGE: English | LEVEL: 2 | ||||
| ECTS CREDITS: 6.0 | YEAR: 4 | SEMESTER: PC | |||
| NAME: SILES RIVAS, EVA | ||
| DEPARTMENT: U103 - BIOLOGÍA EXPERIMENTAL | ||
| FIELD OF STUDY: 060 - BIOQUÍMICA Y BIOLOGÍA MOLECULAR | ||
| OFFICE NO.: B3 - B3-364 | E-MAIL: esiles@ujaen.es | P: 953212705 |
| WEBSITE: https://www.uja.es/investigacion-y-transferencia/grupos-de-investigacion/estres-celular-y-edad | ||
| ORCID: https://orcid.org/0000-0003-4192-7008 | ||
| LANGUAGE: English | LEVEL: 2 | |
| NAME: BEGARA MORALES, JUAN CARLOS | ||
| DEPARTMENT: U103 - BIOLOGÍA EXPERIMENTAL | ||
| FIELD OF STUDY: 060 - BIOQUÍMICA Y BIOLOGÍA MOLECULAR | ||
| OFFICE NO.: B3 - 08 | E-MAIL: jbegara@ujaen.es | P: 953213058 |
| WEBSITE: - | ||
| ORCID: - | ||
| LANGUAGE: English | LEVEL: 2 | |
Theoric curriculum
- Overview of regulation and integration of metabolism.
- Signal transduction systems. cAMP-dependent pathway, inositol polyphosphate-dependent pathway, receptor tyrosine kinases (the insulin receptor), cGMP and nitric oxide-dependent pathways, and steroid hormone receptors.
- Metabolism of carbohydrates, lipids and nitrogenous compounds and its regulation. Glycolisis and gluconeogenesis. Metabolism of glycogen. Pentose phosphate pathway. Digestion, absorption and transport of lipids. Biosynthesis and catabolism of fatty acids. Ketone bodies. Biosynthesis of triacylglycerols and membrane lipids. Metabolism of nucleotides. General aspects of amino acid metabolism. The urea cycle.
- Regulation of gene expression. Regulation of gene expression in prokaryotes: Lactose operon. Arabinose operon. Tryptophan operon. Lysogenic and lytic growth in lambda phage. Small ARNs. Regulation of gene expression in eukaryotes: Chromatin structure and gene expression. Transcription factors and its interaction with DNA. Post-transcriptional regulation.
- Protein folding, maturation, sorting and degradation. Mechanisms of protein folding. Post-translational modifications of proteins. Protein-sorting pathways. Protein degradation: The ubiquitin-proteasome pathway and lysosomal proteolysis.
- Methods for the study of gene and protein expression. Western-blot. Proteomics. Northern-blot. PCR. Real-time PCR. DNA arrays.
Laboratory practice
Effect of starvation on rat-liver glycogen content and glucose 6-phosphate dehydrogenase activity and expression.
This curriculum is connected to SDG-3 (Good-Health and Well Being), SDG-4 (Quality Education), SDG-9(Industry, Innovation and Infraestructure) and SDG-15 (Life and Terrestrial Ecosystems).
Previous knowledge of general biochemistry is highly recommended.
TEACHING METHODOLOGY:
a) Academic sessions to the large group of students: 26 hours (2,6 ECTS)
b) Academic sessions to the small group of students: 32 hours (3,2 ECTS)
c) Collective tutorial sessions: 2 hours (0,2 ECTS)
TEACHING METHODOLOGY FOR PATIE STUDENTS:
a) Lecture (Theory). Tutorial sessions, proposal of activities and exercises, and supply of printted material in English (in presence of professor or virtual), 1 hour per week
b) Lecture (Practice): Explanation of laboratory practice in English, 20 hours
c) Seminars: 0-2 hours per week
c) Homework: 4 hours per week.
Students with special educational needs should contact the Student Attention Service (Servicio de Atención y Ayudas al Estudiante) in order to receive the appropriate academic support
Assessment methodology:
1) Exam of theoric curriculum (50%); 2) compliance with the practices (25%); 3) seminars and other activities (20%) and 4) attendance and active participation (5%)
- Current protocols essential laboratory techniques. Edition: -. Author: -. Publisher: Hoboken, N.J. : John Wiley & Sons, c2008 (Library)
- Textbook of biochemistry : with clinical correlations. Edition: 7 th ed. Author: -. Publisher: Hoboken, N.J : John Wiley &Sons, Inc. , 2011 (Library)
-
Online research articles. Edition: -. Author: -.
- Notes: https://pubmed.ncbi.nlm.nih.gov/
-
BioROM Ayudas al aprendizaje de bioquímica, biotecnología y biología molecular. Edition: -. Author: -.
- Notes: https://www.sebbm.es/BioROM/indices/index.html
- Lehninger Principles of Biochemistry: INTERNATIONAL EDITION. Edition: 8ª. Author: D. L. Nelson, M. Cox. Publisher: W.H.Freeman & Co Ltd (Library)
- Principles of biochemistry. Edition: 5th ed. Author: -. Publisher: Boston : Pearson, c2014 (Library)
- Biochemistry. The Chemical Reactions of Living Cells.. Edition: 2ª. Author: Metzler. Publisher: Harcourt Academic Press (Library)
- Molecular Biology of the cell. Edition: 6ª. Author: Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter. Publisher: Garland Science: New York and Abingdon (Library)
- Harper's illustrated biochemistry Victor W. Rodwell, David A. Bender, Kathleen M. Botham, Peter J. Kennelly, P. Anthony Weil. Edition: 31st ed. Author: Rodwell, Victor W.. Publisher: McGraw Hill Education (Library)
-
Manual en Internet de bioquímica para estudiantes en Ciencias Medicas/The Medical Biochemistry Page. Edition: -. Author: -.
- Notes: https://themedicalbiochemistrypage.org/
TEACHING METHODOLOGY AND TRAINING ACTIVITIES
|
Training activities |
Format (face to face/ online) |
Teaching methodology |
|
Master classes (26 hours) |
Face to face in a percentage that will depend on the socio-sanitary situation. Online for those not face to face (synchronous manner). |
Lectures |
|
Laboratory practices (5 sessions) |
Face to face in a percentage that will depend on the socio-sanitary situation. Online for those not face to face. |
|
|
Seminars (Problem-based learning, 6 sessions) |
F ace to face in a percentage that will depend on the socio-sanitary situation. Online for those not face to face. |
Analysis and resolution of exercises and activities related to the theoretical concepts of the subject. |
|
Tutorial sessions |
Face to face + Online |
Although some sessions could be face to face, most of them will be by videoconference (synchronous), and punctually in an asynchronous manner. |
ASSESSMENT METHODOLOGY
Convocatoria ordinaria
|
Assessment methodology |
Format (face to face/online) |
Description |
Percentage |
|
Attendance and participation in presential or virtual activities |
Face to face, if possible according to the sociosanitary situation, and online |
Attendance and active participation in lectures and seminars |
5% |
|
Theoretical concepts of the subject |
Face to face, if possible according to the sociosanitary situation. If necessary, online. |
Written exam about the knowledge and understanding of the theoretical contents. The students should get more than 4 points out of ten to consider the other aspects of the assessment |
50% |
|
Laboratory practices |
Face to face, if possible according to the sociosanitary situation, and online.
|
Attendance, attitude, interest and the quality of the laboratory report (online) |
25% |
|
Seminars and other activities |
Face to face, if possible according to the sociosanitary situation, and online |
Continuous assessment of the quality of the material prepared (online in an asynchronous manner) and oral presentation to the teacher |
20% |
Convocatoria extraordinaria
|
Assessment methodology |
Format (face to face/online) |
Description |
Percentage |
|
Theoretical concepts of the subject |
Face to face, if possible according to the sociosanitary situation |
Written exam about the knowledge and understanding of the theoretical contents. The students should get more than 4 points out of ten to consider the other aspects of the assessment |
55% |
|
Laboratory practices |
Face to face, if possible according to the sociosanitary situation, and online
|
Quality of the laboratory report (online in an asynchronous manner) and face to face exam if the student hasn´t attended the laboratory practices |
25% |
|
Seminars and other activities |
Face to face, , if possible according to the sociosanitary situation, and online |
Continuous assessment of the quality of the material prepared (online in an asynchronous manner) and oral presentation to the teacher |
20% |
RESOURCES
The use of the electronic bibliographic resources included in the bibliography section of the original course syllabus will be promoted.
Computer resources: teaching platform, e-mail, Google Meet, and any other offered by the University of Jaén.
TEACHING METHODOLOGY AND TRAINING ACTIVITIES
|
Training activities |
Format (face to face/ online) |
Teaching methodology |
|
Master classes (26 hours) |
Online |
Online lectures in a synchronous manner |
|
Laboratory practices (5 sessions) |
Online |
Online activities in an asynchronous and synchronous manner |
|
Seminars (Problem-based learning, 6 sessions) |
Online |
Analysis and resolution of exercises and activities related to the theoretical concepts of the subject (online in a synchronous manner). |
|
Tutorial sessions |
Online |
Tutorial sessions by videoconference (synchronous), and punctually in an asynchronous manner. |
ASSESSMENT METHODOLOGY
Convocatoria ordinaria
|
Assessment methodology |
Format (face to face/online) |
Description |
Percentage |
|
Attendance and participation in presential or virtual activities |
Online |
Attendance and active participation in lectures and seminars (online in a synchronous manner) |
5% |
|
Theoretical concepts of the subject |
Online |
Online synchronous exam about the knowledge and understanding of the theoretical contents. The students should get more than 4 points out of ten to consider the other aspects of the assessment |
50% |
|
Laboratory practices |
Online
|
Attendance, attitude, interest and the quality of the laboratory report (online in a synchronous and asynchronous manner) |
25% |
|
Seminars and other activities |
Online |
Continuous assessment of the quality of the material prepared (online in an asynchronous manner) and oral presentation to the teacher (online in a synchronous manner) |
20% |
Convocatoria extraordinaria
|
Assessment methodology |
Format (face to face/online) |
Description |
Percentage |
|
Theoretical concepts of the subject |
Online |
Written online synchronous exam about the knowledge and understanding of the theoretical contents. The students should get more than 4 points out of ten to consider the other aspects of the assessment |
55% |
|
Laboratory practices |
Online |
Quality of the laboratory report (online in an asynchronous manner) and online synchronous exam is the student hasn´t attended the laboratory practices |
25% |
|
Seminars and other activities |
Online |
Assessment of the quality of the material prepared (online in an asynchronous manner) and oral presentation to the teacher |
20% |
RESOURCES
The use of the electronic bibliographic resources included in the bibliography section of the original course syllabus will be promoted.
Computer resources: teaching platform, e-mail, Google Meet, and any other offered by the University of Jaén.
Institution in charge of data processing: Universidad de Jaén, Campus Las Lagunillas, s/n, 23071 Jaén
Data Protection Delegate: dpo@ujaen.es
Purpose: In accordance with the Universities Law and other national and regional regulations in force, carrying out exams and assessment tests corresponding to the courses students are registered in. In order to avoid frauds while sitting the exam, the exam will be answered using a videoconference system, being able the academic staff of the University of Jaén to compare and contrast the image of the person who is answering the exam with the student's photographic files. Likewise, in order to provide the exam with evidential content for revisions or claims, in accordance with current regulation frameworks, the exam will be recorded and stored.
Legitimacy: compliance with legal obligations (Universities Law) and other national and regional regulations currently in force.
Addressees: service providers who are the owners of the platforms where the exams are carried out and with whom the University of Jaén has signed the corresponding data access contracts.
Storage periods: those established in current in force regulations. In the specific case of exam videoconference recordings, not before the examination records and transcripts are closed or the exam can still be reviewed or challenged.
Rights: you can exercise your right of access, amendment, cancellation, opposition, suppression, limitation and portability by sending a letter to the postal or electronic address indicated above. In the event that you consider that your rights have been violated, you may submit a complaint to the Andalusian Council for Transparency and Data Protection www.ctpdandalucia.es
Person in charge: Universidad de Jaén, Paraje Las Lagunillas, s/n; Tel.953 212121; www.ujaen.es
Data protection delegate (DPO): TELEFÓNICA, S.A.U. ; Email: dpo@ujaen.es
Procedure aim: To manage proper recordings of teaching sessions with the aim of facilitating learning process under a multimodal and/or online teaching
Period for record storage: Images will be kept during legal term according to regulations in force
Legitimacy: Data will be managed according to legal regulations (Organic Law 6/2001, December 21, on Universities) and given consent provided by selecting corresponding box in legal admission documents
Data recipients (transfers or assignments): Any person allowed to get access to every teaching modality
Rights: You may exercise your rights of access, rectification, cancellation, portability, limitation of processing, deletion or, where appropriate, opposition. To exercise these rights, you must submit a written request to the Information, Registration and Electronic Administration Service of the University of Jaen at the address above, or by e-mail to the address above. You must specify which of these rights you are requesting to be satisfied and, at the same time, you must attach a photocopy of your ID card or equivalent identification document. In case you act through a representative, legal or voluntary, you must also provide a document that proves this representation and identification. Likewise, if you consider that your right to personal data protection has been violated, you may file a complaint with the Andalusian Data Protection and Transparency Council www.ctpdandalucia.es