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Syllabus 2020-21 - 76713003 - Cellular Stress (Estrés celular)
- Level 1: Tutorial support sessions, materials and exams in this language
- Level 2: Tutorial support sessions, materials, exams and seminars in this language
- Level 3: Tutorial support sessions, materials, exams, seminars and regular lectures in this language
| DEGREE: | Máster Univ. en Biotecnología y biomedicina (76713003) |
| FACULTY: | Centro de Estudios de Postgrado |
| DEGREE: | Doble Máster en Biotecnología y Biomedicina y MFPES (Profesorado) (77913003) |
| FACULTY: | Centro de Estudios de Postgrado |
| ACADEMIC YEAR: | 2020-21 |
| COURSE: | Cellular Stress |
| NAME: Cellular Stress | |||||
| CODE: 76713003 (*) | ACADEMIC YEAR: 2020-21 | ||||
| LANGUAGE: English | LEVEL: 2 | ||||
| ECTS CREDITS: 3.0 | YEAR: 1 | SEMESTER: SC | |||
| NAME: BARROSO ALBARRACÍN, JUAN BAUTISTA | ||
| DEPARTMENT: U103 - BIOLOGÍA EXPERIMENTAL | ||
| FIELD OF STUDY: 060 - BIOQUÍMICA Y BIOLOGÍA MOLECULAR | ||
| OFFICE NO.: B3 - 347 | E-MAIL: jbarroso@ujaen.es | P: 953-212764 |
| WEBSITE: - | ||
| ORCID: https://orcid.org/0000-0002-9477-9195 | ||
| LANGUAGE: - | LEVEL: 2 | |
This course offers the student an integrated overview of the main mechanisms involved in the processes of mid-cellular defense by reactive oxygen species (ROS) and reactive nitrogen species (RNS). Currently, the involvement of oxygen and nitrogen free radicals in many relevant metabolic processes and are known to be primarily responsible for certain mechanisms of cell damage in living beings, participating in the pathogenesis of different diseases and in numerous situations of stress. In this course we study the production of free radicals of oxygen and reactive nitrogen, as well as the different cellular functions of these oxygen and reactive nitrogen species and their involvement in various pathologies.
1.Biological functions of free oxygen, nitrogen and sulphur radicals in cell metabolism.
- Chemistry of the oxygen molecule: excited forms and reduced forms.
- Oxygen toxicity.
- Biochemical reactivity of nitric oxide.
- Reactive oxygen species (ROS) enzyme.
- Enzymology of reactive nitrogen species (RNS).
- Oxidative stress and nitrosative stress.
- Cell damage and cytotoxicity.
- Subcellular production of oxygen (ROS) and nitrogen (RNS) radicals.
10.Production of oxygen and nitrogen radicals in situations of cellular stress.
11.Role of nitric oxide in biological systems. Biotechnological applications.
12.ROS, RNS and cell signaling in biomedicine.
13.Cellular systems of antioxidant defence. Biotechnological applications.
14.Methodologies for the detection of ROS and RNS in biomedicine.
Large group exhibition classes:
* M1
* M2
* M3
* M4
* M5
*Introductory activities.
*Masterly session.
*Conferences.
Classes in practice groups:
* M 7
* M12
* M8
*Practices.
*Seminars.
*Presentations/exhibitions.
Collective/individual tutorials:
* M14
* M25
* M37
*Supervision of directed work.
*Seminars.
*Debates.
*Clearance of doubts.
*Comments on individual works.
*Presentations/Exhibitions.
Students with special educational needs should contact the Student Attention Service (Servicio de Atención y Ayudas al Estudiante) in order to receive the appropriate academic support
Attendance (10%):
-Active participation in the class.
-Participation in the debates.
-Participation in group work.
-Seminars and defence (60%) : Discussion of the different
thematic contents of the seminar carried out by the student that
allows to evaluate the acquisition of the contents taught
throughout the course, as well as the level of methodological
understanding and the capacity of each student for the
interpretation of the scientific bibliography.
- Practical classes (30%) : Attendance to the practical
classes and delivery of a report of results of the practical
classes that will include a commentary of results and the
discussion of the same with the support of related recent
bibliography. Attendance at the practical classes is compulsory as
well as the delivery of the report through the virtual teaching
platform ILIAS in order to pass the course. In the following calls,
in order to pass the subject, the student must present a report on
the practices as well as hold a seminar and present it, within
those offered in the call for papers. On the other hand, as stated
in the Regulations on the academic regime and evaluation of
students (Article 18.): An announcement will be considered
exhausted when the evaluation tests in which the student has
participated together represent more than 30% of the final
qualification of the subject.
- BIOLOGY of nitric oxide Part 5 editors, S. Moncada ... [et al.]. Edition: -. Author: Moncada, S., ed. lit.. Publisher: Portland Press (Library)
- Cellular and molecular biology of nitric oxide. Edition: -. Author: Laskin, Jeffrey D.. Publisher: Marcel Dekker (Library)
- Free radicals, nitric oxide, and inflammation [electronic resource] : molecular, biochemical, and clinical aspects edited by Aldo Tomasi, Tomris Ozben, and Vladimir P. Skulachev.. Edition: -. Author: Tomasi, Aldo.. Publisher: IOS Press (Library)
- Biología Molecular y Celular Juan Peragón Sánchez y MªÁngeles Peinado Herreros (eds). Edition: -. Author: Peragón Sánchez, Juan.. Publisher: Editorial Universidad de Jaén (Library)
- Biología Molecular y Celular [Recurso electrónico] : Volumen II : Biomedicina Juan Peragón Sánchez y MªÁngeles Peinado Herreros (eds). Edition: -. Author: Peragón Sánchez, Juan.. Publisher: Editorial Universidad de Jaén (Library)
1.-DESCRIPTION
Multimodal Scenario
|
Training Activities |
Format (face-to-face/online)* |
Teaching methodology Description |
|
A1- Large Group Exhibition Classes M2 - Exposure of theory and general examples |
Based on the usual number of students and given the optional nature of the subject, it will be possible to develop 100% attendance. However, if the circumstances may make it advisable, the required sessions will be moved to online format. |
10 sessions of master classes of 1.5 hours and 1 session of 2.0 hours given by the teaching staff to the large group |
|
A2-Classes in practice groups M7-Laboratories |
Based on the usual number of students and given the optional nature of the subject, it will be possible to develop the attendance at 100%. However, if the circumstances may make it advisable, the required sessions will be moved to online format. |
2 sessions of laboratory practices of 4 hours duration, and 1 session of 2 hours duration, given by the teaching staff to the small laboratory group. |
|
A2- Classes in practice groups M12- Student presentations / exhibitions |
Based on the usual number of students and given the optional nature of the subject, it will be possible to develop the attendance at 100%. However, if the circumstances may make it advisable, the required sessions will be moved to online format. |
1 seminar presentation session by students lasting 3 hours in the classroom. |
|
A3- tutorías colectivas
|
100% Online |
All tutoring sessions will be conducted online (synchronous and asynchronous). |
2- EVALUATION SYSTEM
Multimodal Scenario
Ordinary call
|
Aspect |
Assessment test |
Format (face-to-face/online synchronous or asynchronous) |
Description |
Percentage |
|
Attendance and/or participation |
control Attendance |
Synchronous attendance |
Attendance at the face-to-face teaching sessions. Participation in the debates. |
10% |
|
Carrying out of works, cases or exercises |
Carrying out of Seminars by the students and defence of the same |
Synchronous attendance |
Discussion of the different thematic contents of the seminar carried out by the students that allows to evaluate the acquisition of the contents taught throughout the course, as well as the level of methodological understanding and the capacity of each student for the interpretation of the scientific bibliography. |
60% |
|
Laboratory practices |
Delivery of the practice report in electronic format. |
Synchronous attendance |
Synchronous attendance to the practical classes sessions and delivery of a report that will include a commentary of results and the discussion of them with the support of recent related bibliography. It is considered compulsory both to attend the online practical class sessions and to submit the report through the virtual teaching platform ILIAS in order to pass the course. |
30% |
Extraordinary call
|
Aspect |
Assessment test |
Format (face-to-face/online synchronous or asynchronous) |
Description |
Percentage |
|
Attendance and/or participation |
control Attendance |
Synchronous attendance |
Attendance at the face-to-face teaching sessions. Participation in the debates. |
10% |
|
Carrying out of works, cases or exercises |
Carrying out of Seminars by the students and defence of the same |
Synchronous attendance |
Discussion of the different thematic contents of the seminar carried out by the students that allows to evaluate the acquisition of the contents taught throughout the course, as well as the level of methodological understanding and the capacity of each student for the interpretation of the scientific bibliography. |
60% |
|
Laboratory practices |
Delivery of the practice report in electronic format. |
Synchronous attendance |
Synchronous attendance to the practical classes sessions and delivery of a report that will include a commentary of results and the discussion of them with the support of recent related bibliography. It is considered compulsory both to attend the online practical class sessions and to submit the report through the virtual teaching platform ILIAS in order to pass the course. |
30% |
3. RESOURCES
- Google tools (Meet, Forms, Calendar, etc).
- The ILIAS virtual teaching platform of the University of
Jaén.
- The e-mail.
- Internet resources: videos, bibliography, others.
1.-DESCRIPTION
Non-presence scenario
|
Training Activities |
Format (face-to-face/online)* |
Teaching methodology Description |
|
A1- Large Group Exhibition Classes M2 - Exposure of theory and general examples |
100% Online |
10 sessions of master classes of 1.5 hours and 1 session of 2.0 hours given by the teaching staff to the large group |
|
A2-Classes in practice groups M7-Laboratories |
100% Online |
2 laboratory practice sessions of 4 hours, and 1 practical session of 2 hours, given by the teaching staff synchronously and online via videoconference to the group |
|
A2- Classes in practice groups M12- Student presentations / exhibitions |
100% Online |
1 seminar session by students of 3 hours duration, developed in a synchronous way and online through videoconference. |
|
A3- tutorías colectivas
|
100% Online |
All tutoring sessions will be conducted online (synchronous and asynchronous). |
2- EVALUATION SYSTEM
Non-presence scenario
Ordinary call
|
Aspect |
Assessment test |
Format (face-to-face/online synchronous or asynchronous) |
Description |
Percentage |
|
Attendance and/or participation |
control Attendance |
100% Online |
Attendance at the teaching sessions. Participation in the debates. |
10% |
|
Carrying out of works, cases or exercises |
Carrying out of Seminars by the students and defence of the same |
100% Online |
Discussion of the different thematic contents of the seminar carried out by the students that allows to evaluate the acquisition of the contents taught throughout the course, as well as the level of methodological understanding and the capacity of each student for the interpretation of the scientific bibliography. |
60% |
|
Laboratory practices |
Delivery of the practice report in electronic format. |
100% Online |
Synchronous attendance to the practical classes sessions and delivery of a report that will include a commentary of results and the discussion of them with the support of recent related bibliography. It is considered compulsory both to attend the online practical class sessions and to submit the report through the virtual teaching platform ILIAS in order to pass the course. |
30% |
Extraordinary call
|
Aspect |
Assessment test |
Format (face-to-face/online synchronous or asynchronous) |
Description |
Percentage |
|
Attendance and/or participation |
control Attendance |
100% Online |
Attendance at the teaching sessions. Participation in the debates. |
10% |
|
Carrying out of works, cases or exercises |
Carrying out of Seminars by the students and defence of the same |
100% Online |
Discussion of the different thematic contents of the seminar carried out by the students that allows to evaluate the acquisition of the contents taught throughout the course, as well as the level of methodological understanding and the capacity of each student for the interpretation of the scientific bibliography. |
60% |
|
Laboratory practices |
Delivery of the practice report in electronic format. |
100% Online |
Synchronous attendance to the practical classes sessions and delivery of a report that will include a commentary of results and the discussion of them with the support of recent related bibliography. It is considered compulsory both to attend the online practical class sessions and to submit the report through the virtual teaching platform ILIAS in order to pass the course. |
30% |
3. RESOURCES
- Google tools (Meet, Forms, Calendar, etc).
- The ILIAS virtual teaching platform of the University of
Jaén.
- The e-mail.
- Internet resources: videos, bibliography, others.
Institution in charge of data processing: Universidad de Jaén, Campus Las Lagunillas, s/n, 23071 Jaén
Data Protection Delegate: dpo@ujaen.es
Purpose: In accordance with the Universities Law and other national and regional regulations in force, carrying out exams and assessment tests corresponding to the courses students are registered in. In order to avoid frauds while sitting the exam, the exam will be answered using a videoconference system, being able the academic staff of the University of Jaén to compare and contrast the image of the person who is answering the exam with the student's photographic files. Likewise, in order to provide the exam with evidential content for revisions or claims, in accordance with current regulation frameworks, the exam will be recorded and stored.
Legitimacy: compliance with legal obligations (Universities Law) and other national and regional regulations currently in force.
Addressees: service providers who are the owners of the platforms where the exams are carried out and with whom the University of Jaén has signed the corresponding data access contracts.
Storage periods: those established in current in force regulations. In the specific case of exam videoconference recordings, not before the examination records and transcripts are closed or the exam can still be reviewed or challenged.
Rights: you can exercise your right of access, amendment, cancellation, opposition, suppression, limitation and portability by sending a letter to the postal or electronic address indicated above. In the event that you consider that your rights have been violated, you may submit a complaint to the Andalusian Council for Transparency and Data Protection www.ctpdandalucia.es
Person in charge: Universidad de Jaén, Paraje Las Lagunillas, s/n; Tel.953 212121; www.ujaen.es
Data protection delegate (DPO): TELEFÓNICA, S.A.U. ; Email: dpo@ujaen.es
Procedure aim: To manage proper recordings of teaching sessions with the aim of facilitating learning process under a multimodal and/or online teaching
Period for record storage: Images will be kept during legal term according to regulations in force
Legitimacy: Data will be managed according to legal regulations (Organic Law 6/2001, December 21, on Universities) and given consent provided by selecting corresponding box in legal admission documents
Data recipients (transfers or assignments): Any person allowed to get access to every teaching modality
Rights: You may exercise your rights of access, rectification, cancellation, portability, limitation of processing, deletion or, where appropriate, opposition. To exercise these rights, you must submit a written request to the Information, Registration and Electronic Administration Service of the University of Jaen at the address above, or by e-mail to the address above. You must specify which of these rights you are requesting to be satisfied and, at the same time, you must attach a photocopy of your ID card or equivalent identification document. In case you act through a representative, legal or voluntary, you must also provide a document that proves this representation and identification. Likewise, if you consider that your right to personal data protection has been violated, you may file a complaint with the Andalusian Data Protection and Transparency Council www.ctpdandalucia.es