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Syllabus 2020-21 - 10213004 - Metabolic and Molecular Biochemistry (Bioquímica metabólica y molecular)

Caption
  • Level 1: Tutorial support sessions, materials and exams in this language
  • Level 2: Tutorial support sessions, materials, exams and seminars in this language
  • Level 3: Tutorial support sessions, materials, exams, seminars and regular lectures in this language
DEGREE: Grado en Biología
FACULTY: FACULTY OF EXPERIMENTAL SCIENCES
ACADEMIC YEAR: 2020-21
COURSE: Metabolic and Molecular Biochemistry
SYLLABUS
1. COURSE BASIC INFORMATION
NAME: Metabolic and Molecular Biochemistry
CODE: 10213004 ACADEMIC YEAR: 2020-21
LANGUAGE: English LEVEL: 2
ECTS CREDITS: 6.0 YEAR: 4 SEMESTER: PC
2. LECTURER BASIC INFORMATION
NAME: SILES RIVAS, EVA
DEPARTMENT: U103 - BIOLOGÍA EXPERIMENTAL
FIELD OF STUDY: 060 - BIOQUÍMICA Y BIOLOGÍA MOLECULAR
OFFICE NO.: B3 - B3-364 E-MAIL: esiles@ujaen.es P: 953212705
WEBSITE: https://www.uja.es/investigacion-y-transferencia/grupos-de-investigacion/estres-celular-y-edad
ORCID: https://orcid.org/0000-0003-4192-7008
LANGUAGE: English LEVEL: 2
NAME: PERAGÓN SÁNCHEZ, JUAN
DEPARTMENT: U103 - BIOLOGÍA EXPERIMENTAL
FIELD OF STUDY: 060 - BIOQUÍMICA Y BIOLOGÍA MOLECULAR
OFFICE NO.: B3 - 356 E-MAIL: jperagon@ujaen.es P: 953212523
WEBSITE: www4.ujaen.es/~jperagon/
ORCID: https://orcid.org/0000-0002-7502-1119
LANGUAGE: English LEVEL: 2
3. CONTENT DESCRIPTION

Theoric curriculum

  1. Overview of regulation and integration of metabolism.
  2. Signal transduction systems. cAMP-dependent pathway, inositol polyphosphate-dependent pathway, receptor tyrosine kinases (the insulin receptor), cGMP and nitric oxide-dependent pathways, and steroid hormone receptors.
  3. Metabolism of carbohydrates, lipids and nitrogenous compounds and its regulation. Glycolisis and gluconeogenesis. Metabolism of glycogen. Pentose phosphate pathway. Digestion, absorption and transport of lipids. Biosynthesis and catabolism of fatty acids. Ketone bodies. Biosynthesis of triacylglycerols and  membrane lipids. Metabolism of nucleotides. General aspects of amino acid metabolism. The urea cycle.
  4. Regulation of gene expression. Regulation of gene expression in prokaryotes: Lactose operon. Arabinose operon. Tryptophan operon. Lysogenic and lytic growth in lambda phage. Small ARNs. Regulation of gene expression in eukaryotes: Chromatin structure and gene expression. Transcription factors and its interaction with DNA. Post-transcriptional regulation.
  5. Protein folding, maturation, sorting and degradation. Mechanisms of protein folding. Post-translational modifications of proteins. Protein-sorting pathways. Protein degradation: The ubiquitin-proteasome pathway and lysosomal proteolysis.
  6. Methods for the study of  gene and protein expression.  Western-blot. Proteomics. Northern-blot. PCR. Real-time PCR. DNA arrays.  

Laboratory practice

Effect of starvation on rat-liver glycogen content and glucose 6-phosphate dehydrogenase activity and expression.

4. COURSE DESCRIPTION AND TEACHING METHODOLOGY

TEACHING METHODOLOGY:

a) Academic sessions to the great group of students: 26 hours (2,6 ECTS)

b) Academic sessions to the small group of students: 32 hours (3,2 ECTS)

c) Collective tutorial sessions: 2 hours (0,2 ECTS)

TEACHING METHODOLOGY FOR PATIE STUDENTS:

a)  Lecture (Theory). Tutorial sessions, proposal of activities and exercises, and supply of printted material in English (in presence of professor or virtual), 1 hour per week

b) Lecture (Practice): Explanation of laboratory practice in English, 20 hours

c) Seminars: 0-2 hours per week

c) Homework: 4 hours per week.

 

Students with special educational needs should contact the Student Attention Service (Servicio de Atención y Ayudas al Estudiante) in order to receive the appropriate academic support

5. ASSESSMENT METHODOLOGY

Assessment methodology:

1) Exam of theoric curriculum (50%); 2) compliance with the practices (25%) and 3) seminars and other activities (20%); attendance and active participation (5%)

6. BOOKLIST
MAIN BOOKLIST:
  • Current protocols essential laboratory techniques. Edition: -. Author: -. Publisher: Hoboken, N.J. : John Wiley & Sons, c2008  (Library)
  • Textbook of biochemistry : with clinical correlations. Edition: 7 th ed. Author: -. Publisher: Hoboken, N.J : John Wiley &Sons, Inc. , 2011  (Library)
  • Online research articles. Edition: -. Author: -.
    • Notes: https://pubmed.ncbi.nlm.nih.gov/
  • BioROM Ayudas al aprendizaje de bioquímica, biotecnología y biología molecular. Edition: -. Author: -.
    • Notes: https://www.sebbm.es/BioROM/indices/index.html
  • Lehninger Principles of Biochemistry. Edition: 7ª. Author: David L. Nelson; Michael M. Cox. Publisher: W H FREEMAN & CO,  (Library)
ADDITIONAL BOOKLIST:
  • Molecular cell biology. Edition: 6th ed., 1st print.. Author: -. Publisher: New York : W. H. Freeman and Co., cop. 2008  (Library)
  • Harper's illustrated biochemistry. Edition: 27th ed. Author: -. Publisher: New York (etc.): McGraw-Hill, 2006  (Library)
  • Principles of biochemistry. Edition: 5th ed. Author: -. Publisher: Boston : Pearson, c2014  (Library)
  • Biochemistry. The Chemical Reactions of Living Cells.. Edition: 2ª. Author: Metzler. Publisher: Harcourt Academic Press  (Library)
  • Molecular Biology of the cell. Edition: 6ª. Author: Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter. Publisher: Garland Science: New York and Abingdon  (Library)
7. VIRTUAL / CLASSROOM TEACHING SCENARIO

TEACHING METHODOLOGY AND TRAINING ACTIVITIES

Training activities

Format (face to face/ online)

Teaching methodology

Master classes (26 hours)

Online

Online lectures in a synchronous manner

Laboratory practices (5 sessions)

Face to face 50% if possible according to the sociosanitary situation

  1. a) Laboratory practices: 3 sessions face to face (2 of 4h and 1 of 2h).
  2. b) Online activities in an asynchronous manner

Seminars (Problem-based learning, 6 sessions)

Face to face 100% if possible according to the sociosanitary situation

Analysis and resolution of exercises and activities  related to the theoretical concepts of the subject

Tutorial sessions

Face to face + Online

Although some sessions could be face to face, most of them will be  by videoconference (synchronous), and punctually in an  asynchronous manner.

 

ASSESSMENT METHODOLOGY

 

Convocatoria ordinaria

Assessment methodology

Format (face to face/online)

Description

Percentage

Attendance and participation in presential or virtual activities

Face to face, if possible according to the sociosanitary situation, and online

Attendance and active participation in lectures and seminars

5%

Theoretical concepts of the subject

Face to face, if possible according to the sociosanitary situation

Written exam about the knowledge and understanding of the theoretical contents. The students should get more than  4 points out of ten to consider de other aspects of the assessment

50%

Laboratory practices

Face to face, if possible according to the sociosanitary situation, and online

 

 

Attendance, attitude, interest (face to face) and the quality of the laboratory report (online)

25%

Seminars and other activities

Face to face, if possible according to the sociosanitary situation, and online

Continuous assessment of the quality of the material prepared (online in an asynchronous manner) and oral presentation to the teacher

20%

 

Convocatoria extraordinaria

 

Assessment methodology

Format (face to face/online)

Description

Percentage

Theoretical concepts of the subject

Face to face, if possible according to the sociosanitary situation

Written exam about the knowledge and understanding of the theoretical contents. The students should get more than  4 points out of ten to consider de other aspects of the assessment

55%

Laboratory practices

Face to face, if possible according to the sociosanitary situation,  and online

 

 

Quality of the laboratory report (online in an asynchronous manner) and face to face exam is the student hasn´t attended the laboratory practices

25%

Seminars and other activities

Face to face, , if possible according to the sociosanitary situation, and online

Continuous assessment of the quality of the material prepared (online in an asynchronous manner) and oral presentation to the teacher

20%

 

RESOURCES

The use of the electronic bibliographic resources included in the bibliography section of the original course syllabus will be promoted.

Computer resources: ILIAS teaching platform, e-mail, Google Meet, and any other offered by the University of Jaén.

8. VIRTUAL TEACHING SCENARIO

 

TEACHING METHODOLOGY AND TRAINING ACTIVITIES

Training activities

Format (face to face/ online)

Teaching methodology

Master classes (26 hours)

Online

Online lectures in a synchronous manner

Laboratory practices (5 sessions)

Online

Online activities in an asynchronous and synchronous manner

Seminars (Problem-based learning, 6 sessions)

Online

Analysis and resolution of exercises and activities related to the theoretical concepts of the subject (online in a synchronous manner).

Tutorial sessions

Online

Tutorial sessions by videoconference (synchronous), and punctually in an  asynchronous manner.

 

ASSESSMENT METHODOLOGY

 

Convocatoria ordinaria

Assessment methodology

Format (face to face/online)

Description

Percentage

Attendance and participation in presential or virtual activities

Online

Attendance and active participation in lectures and seminars (online in a synchronous manner)

5%

Theoretical concepts of the subject

Online

Online synchronous exam about the knowledge and understanding of the theoretical contents. The students should get more than  4 points out of ten to consider de other aspects of the assessment

50%

Laboratory practices

Online

 

 

Attendance, attitude, interest and the quality of the laboratory report (online in a synchronous and asynchronous manner)

25%

Seminars and other activities

Online

Continuous assessment of the quality of the material prepared (online in an asynchronous manner) and oral presentation to the teacher (online in a synchronous manner)

20%

 

Convocatoria extraordinaria

 

Assessment methodology

Format (face to face/online)

Description

Percentage

Theoretical concepts of the subject

Online

Written online synchronous exam about the knowledge and understanding of the theoretical contents. The students should get more than  4 points out of ten to consider de other aspects of the assessment

55%

Laboratory practices

Online

Quality of the laboratory report (online in an asynchronous manner) and online synchronous  exam is the student hasn´t attended the laboratory practices

25%

Seminars and other activities

Online

Assessment of the quality of the material prepared (online in an asynchronous manner) and oral presentation to the teacher

20%

 

RESOURCES

The use of the electronic bibliographic resources included in the bibliography section of the original course syllabus will be promoted.

Computer resources: ILIAS teaching platform, e-mail, Google Meet, and any other offered by the University of Jaén.

 

 

DATA PROTECTION CLAUSE (on line exams)

Institution in charge of data processing: Universidad de Jaén, Campus Las Lagunillas, s/n, 23071 Jaén

Data Protection Delegate: dpo@ujaen.es

Purpose: In accordance with the Universities Law and other national and regional regulations in force, carrying out exams and assessment tests corresponding to the courses students are registered in. In order to avoid frauds while sitting the exam, the exam will be answered using a videoconference system, being able the academic staff of the University of Jaén to compare and contrast the image of the person who is answering the exam with the student's photographic files. Likewise, in order to provide the exam with evidential content for revisions or claims, in accordance with current regulation frameworks, the exam will be recorded and stored.

Legitimacy: compliance with legal obligations (Universities Law) and other national and regional regulations currently in force.

Addressees: service providers who are the owners of the platforms where the exams are carried out and with whom the University of Jaén has signed the corresponding data access contracts.

Storage periods: those established in current in force regulations. In the specific case of exam videoconference recordings, not before the examination records and transcripts are closed or the exam can still be reviewed or challenged.

Rights: you can exercise your right of access, amendment, cancellation, opposition, suppression, limitation and portability by sending a letter to the postal or electronic address indicated above. In the event that you consider that your rights have been violated, you may submit a complaint to the Andalusian Council for Transparency and Data Protection www.ctpdandalucia.es

CLASS RECORDING CLAUSE PERSONAL DATA PROTECTION

Person in charge: Universidad de Jaén, Paraje Las Lagunillas, s/n; Tel.953 212121; www.ujaen.es

Data protection delegate (DPO): TELEFÓNICA, S.A.U. ; Email: dpo@ujaen.es

Procedure aim: To manage proper recordings of teaching sessions with the aim of facilitating learning process under a multimodal and/or online teaching

Period for record storage: Images will be kept during legal term according to regulations in force

Legitimacy: Data will be managed according to legal regulations (Organic Law 6/2001, December 21, on Universities) and given consent provided by selecting corresponding box in legal admission documents

Data recipients (transfers or assignments): Any person allowed to get access to every teaching modality

Rights: You may exercise your rights of access, rectification, cancellation, portability, limitation of processing, deletion or, where appropriate, opposition. To exercise these rights, you must submit a written request to the Information, Registration and Electronic Administration Service of the University of Jaen at the address above, or by e-mail to the address above. You must specify which of these rights you are requesting to be satisfied and, at the same time, you must attach a photocopy of your ID card or equivalent identification document. In case you act through a representative, legal or voluntary, you must also provide a document that proves this representation and identification. Likewise, if you consider that your right to personal data protection has been violated, you may file a complaint with the Andalusian Data Protection and Transparency Council www.ctpdandalucia.es