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Syllabus 2019-20 - 10313013 - Natural Products Chemistry (Química de los productos naturales)

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  • Level 1: Tutorial support sessions, materials and exams in this language
  • Level 2: Tutorial support sessions, materials, exams and seminars in this language
  • Level 3: Tutorial support sessions, materials, exams, seminars and regular lectures in this language
DEGREE: Grado en Químicas
FACULTY: FACULTY OF EXPERIMENTAL SCIENCES
ACADEMIC YEAR: 2019-20
COURSE: Natural Products Chemistry
SYLLABUS
1. COURSE BASIC INFORMATION
NAME: Natural Products Chemistry
CODE: 10313013 ACADEMIC YEAR: 2019-20
LANGUAGE: English LEVEL: 1
ECTS CREDITS: 6.0 YEAR: 4 SEMESTER: SC
2. LECTURER BASIC INFORMATION
NAME: SALIDO RUIZ, SOFÍA
DEPARTMENT: U128 - QUÍMICA INORGÁNICA Y ORGÁNICA
FIELD OF STUDY: 765 - QUÍMICA ORGÁNICA
OFFICE NO.: B3 - 465 E-MAIL: ssalido@ujaen.es P: 953-212746
WEBSITE: -
ORCID: https://orcid.org/0000-0003-2319-7873
LANGUAGE: English LEVEL: 1
NAME: ALTAREJOS CABALLERO, JOAQUÍN
DEPARTMENT: U128 - QUÍMICA INORGÁNICA Y ORGÁNICA
FIELD OF STUDY: 765 - QUÍMICA ORGÁNICA
OFFICE NO.: B3 - 444 E-MAIL: jaltare@ujaen.es P: 953212743
WEBSITE: --
ORCID: https://orcid.org/0000-0002-5532-8535
LANGUAGE: English LEVEL: 1
3. CONTENT DESCRIPTION

1.INTRODUCTION. Chemistry of the natural products. Primary and secondary metabolites. Biosynthetic pathways and classification. 2.  SOURCES OF NATURAL PRODUCTS. Plant and animal kingdom. Marine natural products. Microorganisms. Semiochemicals. 3.  ISOLATION, PURIFICATION AND IDENTIFICATION OF NATURAL PRODUCTS. Essential oils. Extracts. Chromatographic separation and purification. Biological activities screening. Structural elucidation. 4.  SEMISYNTHESIS OF CHIRAL COMPOUNDS FROM NATURAL PRODUCTS The chiron approach. Stereoselective reactions. Enzyme transformations. 5. APPLICATION OF NATURAL PRODUCTS ON FOODS AND FRAGRANCES. Phenolic compounds with antioxidant properties: flavonoids, lignans and tannins. Terpenoids: flavours and fragrances. 6.  APPLICATION OF NATURAL PRODUCTS ON MEDICINE. Medicinal plants. Steroids and alkaloids. 7. CARBOHYDRATES. Structure, configuration and conformation of monosaccharides. Reactions of monosaccharides. Structural determination of oligosaccharides. 8. LIPIDS. Fatty acids. Derivatives of fatty acids. Structurally and functionally related compounds with fatty acids. Applications.

Activities of laboratory classes.

Preparation and chromatographic analysis of essential oils and extracts.

Chemical reactions on secondary metabolites.

4. COURSE DESCRIPTION AND TEACHING METHODOLOGY

Students have (i) to attend theory lectures; (ii) to attend laboratory classes, perform the experiments planned by the Lecturer, and prepare a written report on the work developed in the lab; (iii) to search information on a course topic and give a short oral speech; (iv) to visit a research center; (v) to pass a final test on concepts learnt in the course.

Students with special educational needs should contact the Student Attention Service (Servicio de Atención y Ayudas al Estudiante) in order to receive the appropriate academic support

5. ASSESSMENT METHODOLOGY

Ordinary date

(i) Attendance theory lectures: 5%. (ii) Attendance laboratory classes, good performance of experiments, and evaluation of the written report: 20%. (iii) Search for information on chemical databases and give a short oral speech: 10%. (iv) Attendance a visit of a research center: 5%. (v) Final test on concepts learnt in the course: 60%.

Extraordinary date

The student could choose between two options:

a) The same described on the ordinary date.

b) Final test on concepts learnt in the course: 100%.

 

6. BOOKLIST
MAIN BOOKLIST:
  • Medicinal natural products: a biosynthetic approach. Edition: 2nd ed. Author: Dewick, Paul M.. Publisher: Chichester: John Wiley & Sons, cop. 2002  (Library)
ADDITIONAL BOOKLIST:
  • Molecules that changed the world: a brief history of the art and science of synthesis and its impac. Edition: -. Author: Nicolaou, K.C.. Publisher: Weinheim : Wiley-VCH Gmbh&Co. KGaA , cop. 2008.
    • Notes: Tema 1
     (Library)
  • Bioactive marine natural products. Edition: -. Author: Bhakuni, D. S.. Publisher: New York: Springer ; New Delhi: Anamaya, 2005.
    • Notes: Tema 2
     (Library)
  • The chemistry of fragrances. Edition: -. Author: -. Publisher: Cambridge: The Royal Society of Chemistry, 2006.
    • Notes: Tema 3 y 5
     (Library)
  • Lipid analysis: isolation, separation, identification and structural analysis of lipids. Edition: 3rd ed. Author: Christie, William W.. Publisher: Bridgwater: The Oily Press, cop. 2003.
    • Notes: Tema 3
     (Library)
  • Laboratory handbook for fractionation of natural extracts. Edition: London: Chapman & Hall, 1998. Author: Houghton, Peter J.. Publisher: -.
    • Notes: Tema 3
     (Library)
  • Natural products: their chemistry and biological significance. Edition: -. Author: -. Publisher: Essex: Longman, 1998.
    • Notes: Tema 4
     (Library)