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Syllabus 2019-20 - 10213006 - Biological Bases of Human Reproduction (Bases biológicas de la reproducción humana)

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  • Level 1: Tutorial support sessions, materials and exams in this language
  • Level 2: Tutorial support sessions, materials, exams and seminars in this language
  • Level 3: Tutorial support sessions, materials, exams, seminars and regular lectures in this language
DEGREE: Grado en Biología
FACULTY: FACULTY OF EXPERIMENTAL SCIENCES

ACADEMIC YEAR: 2019-20
SYLLABUS
1. COURSE BASIC INFORMATION
NAME: Biological Bases of Human Reproduction
CODE: 10213006 ACADEMIC YEAR: 2019-20
LANGUAGE: English LEVEL: 2
ECTS CREDITS: 6.0 YEAR: 4 SEMESTER: SC
 
2. LECTURER BASIC INFORMATION
NAME: TORRES LÓPEZ, MARÍA ISABEL
DEPARTMENT: U103 - BIOLOGÍA EXPERIMENTAL
FIELD OF STUDY: 050 - BIOLOGÍA CELULAR
OFFICE NO.: B3 - B3-361 E-MAIL: mitorres@ujaen.es P: 212762
WEBSITE: -
LANGUAGE: English LEVEL: 2
 
3. CONTENT DESCRIPTION

THEORETICAL CONTENTS

 

Topic 1. Biological bases of Human Reproduction. Endocrine system. Male reproductive system. Female reproductive system.

 

Topic 2. Gametogenesis Spermatogenesis Oogenesis Ovulation. Endocrine control of ovulation

 

Topic 3. Fertilization. Embryonic development. Sperm and ovule transport. Sperm training and activation. Phases of embryonic development. Gastrulation Neurulation Organogenesis

 

Topic 4 . Bases of Sterility. Identification of the causes of infertility. Female infertility. Male infertility Special categories of infertility: genetic infertility and immunological infertility. Sterility diagnosis. Female sterility treatment

 

 

Topic 5 . Analysis of semen. Seminal analysis and sperm tests. Bank of semen

 

Topic 6. Assisted Reproduction Techniques: artificial insemination, "in vitro" fertilization, sperm microinjection. MACS transfer. IMSI. "Hatching" assisted

 

Topic 7. In Vitro Production of Embryos. Observation and selection of embryos. Embryo culture Co-culture techniques. Freezing and storage of embryos. Defreezing of embryos

 

 

Topic 8 . Multiplication of Embryos and Gametes. Reproductive process Handling. Cloning Nuclear transfer. Cloning techniques. Applications of cloning. Ethical considerations of cloning

 

Topic 9. Determination of Sex Gonadal characteristics. Phenotypic characteristics. Molecular determination of sex. Sex determination techniques

 

 

Topic 10 . Cryobiology Preservation of paternal and maternal inheritance - Preservation of embryos. Microscopic evaluation Vitrification

 

Topic 11. Genetic diagnosis Pre-implantation diagnosis "Screening" aneuploidy

 

Topic 12. Biological Safety and Assisted Reproduction Laboratory. General basics of biological safety. Biological safety in cryopreservation. Transport of reproductive biological material. Action protocols. Evaluation of biological risks

 

Topic 13. Legal and ethical aspects of Assisted Human Reproduction. Spanish and European legislation. Ethical aspects in research and experimentation

 

 

Topic 14 . Basic and applied research in Human Reproduction

 

PRACTICAL CONTENTS

 

Practice 1. Realization of Seminogram. Comparison of fresh and cryopreserved semen samples with different diluents

 

Practice 2. Study of the variations of sperm motility at different pHs. In vitro study

 

Practice 3. Effect of the increase of the temperature on the spermatozoa. In vitro study

 

Practice 4 and 5. Determine the expression of androgen receptors in male reproductive by immunohistochistry

 

Practice 6 and 7 . Determination of the Estrogen Receptor in female reproductive tract by Immunohistochemistry

Practice 8 . Histochemical Study of Female and Male Reproductive

 

Practice 9. Quantification of estrogen expression in ovarian, horn and uterus and androgen receptors in testicle

Practice 10 . Estral cycle of the female mouse

4. COURSE DESCRIPTION AND TEACHING METHODOLOGY

Magistral classes in a large group. Practical laboratory classes in small group. Seminars, exposition of works and debates with problem solving

Students with special educational needs should contact the Student Attention Service (Servicio de Atención y Ayudas al Estudiante) in order to receive the appropriate academic support

5. ASSESSMENT METHODOLOGY

For the evaluation of the theoretical knowledge of the subject a theoretical written probe will be carried out in the official date. The subject of this exam will be eliminated with a grade equal to or higher than 5 out of 10. The mark of the theoretical part represents 60% of the final grade. Through the written exam test we will also evaluate the Skills CT6, CT7, CT8, CT9, CT10 and CG11     

For the evaluation of laboratory practical knowledge, the completion of practices is a mandatory condition. The students must make and present a global notebook of practices in which they respond to the questions that are presented to them and present the results obtained in the practice sessions that will be evaluated and will correspond to 20% of the grade. Those students who do not do the practices will not have the 20% corresponding to practices in the computation of the final grade. In the realization of the sessions of practices will evaluate the Skills CE4, CT2, CT5, CT6, CT7 and CG8 The formative activities will be evaluated by the professor where the realization of the same will be taken into account, as well as the exposition of the works. It assumes 10% of the final grade. Students who do not perform these activities on an ongoing basis may take an oral exam consisting of an exhibition-debate of a topic related to the theoretical or practical contents of the subject. With the accomplishment of the formative activities we will evaluate the skills CE4, CT1, CT2, CT3 and CT4. The attendance to practices and to the formative activities will be evaluated and will suppose 10% of the final note   

It is possible to pass the subject through continuous assessment, without the need for a final theoretical examination, provided that all the academic activities are carried out: theoretical, practical and seminars and are passed with a grade equal to or greater than 5 out of 10.

6. BOOKLIST
MAIN BOOKLIST:
  • Biology of human reproduction. Edition: -. Author: Piñón, Ramón. Publisher: Sausalito, Calif. : University Science Books, cop. 2002  (Library)
  • Essential reproduction. Edition: 6th ed. Author: Johnson, Martin H.. Publisher: Oxford [etc.] : Blackwell Science, 2007  (Library)
  • Cambridge guide to infertility management and assisted reproduction [Recurso electrónico]. Edition: -. Author: Meniru, Godwin I. (Godwin Ikechukwu), 1960-. Publisher: Cambridge, U.K. ; New York : Cambridge University Press, 2001.  (Library)
  • Sperm biology: an evolutionary perspective. Edition: 1st ed.. Author: -. Publisher: Amsterdam ; London : Elsevier Academic Press, 2009.  (Library)
ADDITIONAL BOOKLIST:
  • Environmental impacts on reproductive health and fertility. Edition: -. Author: -. Publisher: Cambridge ; New York : Cambridge University Press, 2010  (Library)
  • Stem cells in human reproduction: basic science and therapeutic potential. Edition: -. Author: -. Publisher: Abingdon, U.K. : Informa Healthcare ; Boca Raton : Taylor & Francis, cop. 2007  (Library)