Universidad de Jaén

1. Cytology and histology in clinical diagnosis:

1.1. Immunohistochemistry (monoclonal and polyclonal antibodies)

1.2. In Situ Hybridization

1. Flow cytometry
2. Biosensors
3. Molecular biology in clinical diagnosis I:

4.1. Quantification of gene expression by real time PCR and its applications

4.2. Real-time PCR for diagnosis

1. Molecular Biology in clinical diagnosis II:

5.1. Next generation DNA sequencing

5.2. SNP genotyping techniques using real time PCR

5.3. Mass genotyping techniques (Veracode, Illumina, etc.)

5.4. Genotyping techniques of copy number variation and microsatellites

5.5. Calculation of haplotypes and genetic risk quantification

5.6. Microarray expression, CGH and microRNAs in clinical diagnosis,  tumor characterization and endometrial receptivity.

1. Analysis of paternity and forensic genetics
2. Genetic counseling and probabilities
3. Production of diagnostic reagents usign biotechnology toos
4. Regulations, laws and patents in molecular diagnostics

Lectures in large group in which the essential theoretical contents will be presented. Invited professors will deliver several classes about clinical diagnostic and biotech business (biosensors, microarrays, mass and clinical genetic sequencing). Practical classes will include immunohistochemical techniques, genetic diagnosis and analysis of genetic data. The students must deliver one seminar. The course also include discussion sessions on practical cases .

Students with special educational needs should contact the Student Attention Service (Servicio de Atención y Ayudas al Estudiante) in order to receive the appropriate academic support

The course is assessed by a variety of methods, including attendance, written examinations, oral presentations, essays, poster preparation and dissertation.