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Syllabus 2018-19 - 76713007 - Biotechnological Methods of Disease Diagnosis (Biotecnología diagnóstica)

Caption
  • Level 1: Tutorial support sessions, materials and exams in this language
  • Level 2: Tutorial support sessions, materials, exams and seminars in this language
  • Level 3: Tutorial support sessions, materials, exams, seminars and regular lectures in this language
DEGREE: Máster Univ. en Biotecnología y biomedicina (76713007)
FACULTY: Centre for Postgraduate Studies of the University of Jaen

DEGREE: Doble Máster en Biotecnología y Biomedicina y MFPES (Profesorado) (77913007)
FACULTY: Centre for Postgraduate Studies of the University of Jaen

ACADEMIC YEAR: 2018-19
SYLLABUS
1. COURSE BASIC INFORMATION
NAME: Biotechnological Methods of Disease Diagnosis
CODE: 76713007 (*) ACADEMIC YEAR: 2018-19
LANGUAGE: English LEVEL: 1
ECTS CREDITS: 3.0 YEAR: 1 SEMESTER: SC
 
2. LECTURER BASIC INFORMATION
NAME: CARUZ ARCOS, ANTONIO JOSÉ
DEPARTMENT: U103 - BIOLOGÍA EXPERIMENTAL
FIELD OF STUDY: 420 - GENÉTICA
OFFICE NO.: B3 - 344 E-MAIL: caruz@ujaen.es P: 953212706
WEBSITE: www.ujaen.es/investiga/inmunoge
LANGUAGE: - LEVEL: 1
 
3. CONTENT DESCRIPTION

  1. Cytology and histology in clinical diagnosis:

1.1. Immunohistochemistry (monoclonal and polyclonal antibodies)

1.2. In Situ Hybridization

  1. Flow cytometry
  2. Biosensors
  3. Molecular biology in clinical diagnosis I:

4.1. Quantification of gene expression by real time PCR and its applications

4.2. Real-time PCR for diagnosis

  1. Molecular Biology in clinical diagnosis II:

5.1. Next generation DNA sequencing

5.2. SNP genotyping techniques using real time PCR

5.3. Mass genotyping techniques (Veracode, Illumina, etc.)

5.4. Genotyping techniques of copy number variation and microsatellites

5.5. Calculation of haplotypes and genetic risk quantification

5.6. Microarray expression, CGH and microRNAs in clinical diagnosis,  tumor characterization and endometrial receptivity.

  1. Analysis of paternity and forensic genetics
  2. Genetic counseling and probabilities
  3. Production of diagnostic reagents usign biotechnology toos
  4. Regulations, laws and patents in molecular diagnostics

4. COURSE DESCRIPTION AND TEACHING METHODOLOGY

Lectures in large group in which the essential theoretical contents will be presented. Invited professors will deliver several classes about clinical diagnostic and biotech business (biosensors, microarrays, mass and clinical genetic sequencing). Practical classes will include immunohistochemical techniques, genetic diagnosis and analysis of genetic data. The students must deliver one seminar. The course also include discussion sessions on practical cases .

Students with special educational needs should contact the Student Attention Service (Servicio de Atención y Ayudas al Estudiante) in order to receive the appropriate academic support

5. ASSESSMENT METHODOLOGY

The course is assessed by a variety of methods, including attendance, written examinations, oral presentations, essays, poster preparation and dissertation. 

6. BOOKLIST
MAIN BOOKLIST:
  • Clinical Genomics. Edition: -. Author: -. Publisher: London [etc.] : Academic Press, cop. 2014  (Library)
  • Molecular cloning : a laboratory manual. Edition: 4th ed. Author: Green, Michael R. Michael Richard, 1954-. Publisher: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, 2012  (Library)
  • Human molecular genetics. Edition: 4th ed.. Author: Strachan, T.. Publisher: New York : Garland Science Taylor & Francis Group, c2010.  (Library)
  • Clinical Genomics. Edition: -. Author: -. Publisher: London [etc.] : Academic Press, cop. 2014  (Library)
  • Molecular cloning : a laboratory manual. Edition: 4th ed. Author: Green, Michael R. Michael Richard, 1954-. Publisher: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, 2012  (Library)
  • Human molecular genetics. Edition: 4th ed.. Author: Strachan, T.. Publisher: New York : Garland Science Taylor & Francis Group, c2010.  (Library)
  • Clinical Genomics. Edition: -. Author: -. Publisher: London [etc.] : Academic Press, cop. 2014  (Library)
  • Molecular cloning : a laboratory manual. Edition: 4th ed. Author: Green, Michael R. Michael Richard, 1954-. Publisher: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, 2012  (Library)
  • Human molecular genetics. Edition: 4th ed.. Author: Strachan, T.. Publisher: New York : Garland Science Taylor & Francis Group, c2010.  (Library)
  • Clinical Genomics. Edition: -. Author: -. Publisher: London [etc.] : Academic Press, cop. 2014  (Library)
  • Molecular cloning : a laboratory manual. Edition: 4th ed. Author: Green, Michael R. Michael Richard, 1954-. Publisher: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, 2012  (Library)
  • Human molecular genetics. Edition: 4th ed.. Author: Strachan, T.. Publisher: New York : Garland Science Taylor & Francis Group, c2010.  (Library)
ADDITIONAL BOOKLIST:
  • Apoptosis, Cell Signaling, and Human Diseases [Recurso electrónico] : Molecular Mechanisms. Edition: -. Author: Srivastava, Rakesh. Publisher: Totowa, NJ : Humana Press Inc., 2007.  (Library)
  • In situ detection of DNA damage: methods and protocols. Edition: -. Author: -. Publisher: Totowa: Humana Press, cop. 2002  (Library)
  • Flow Cytometry [Recurso electrónico] : Principles and Applications. Edition: -. Author: Macey, Marion G.. Publisher: Totowa, NJ : Humana Press Inc., 2007.  (Library)
  • Clinical Applications of PCR [Recurso electrónico] . Edition: -. Author: Lo, Y. M. Dennis. Publisher: Totowa, NJ : Humana Press Inc., 2006.  (Library)
  • Current protocols in molecular biology. Edition: -. Author: -. Publisher: [United States]: John Wiley and Sons, cop. 1998-  (Library)
  • Apoptosis, Cell Signaling, and Human Diseases [Recurso electrónico] : Molecular Mechanisms. Edition: -. Author: Srivastava, Rakesh. Publisher: Totowa, NJ : Humana Press Inc., 2007.  (Library)
  • In situ detection of DNA damage: methods and protocols. Edition: -. Author: -. Publisher: Totowa: Humana Press, cop. 2002  (Library)
  • Flow Cytometry [Recurso electrónico] : Principles and Applications. Edition: -. Author: Macey, Marion G.. Publisher: Totowa, NJ : Humana Press Inc., 2007.  (Library)
  • Clinical Applications of PCR [Recurso electrónico] . Edition: -. Author: Lo, Y. M. Dennis. Publisher: Totowa, NJ : Humana Press Inc., 2006.  (Library)
  • Current protocols in molecular biology. Edition: -. Author: -. Publisher: [United States]: John Wiley and Sons, cop. 1998-  (Library)
  • Apoptosis, Cell Signaling, and Human Diseases [Recurso electrónico] : Molecular Mechanisms. Edition: -. Author: Srivastava, Rakesh. Publisher: Totowa, NJ : Humana Press Inc., 2007.  (Library)
  • In situ detection of DNA damage: methods and protocols. Edition: -. Author: -. Publisher: Totowa: Humana Press, cop. 2002  (Library)
  • Flow Cytometry [Recurso electrónico] : Principles and Applications. Edition: -. Author: Macey, Marion G.. Publisher: Totowa, NJ : Humana Press Inc., 2007.  (Library)
  • Clinical Applications of PCR [Recurso electrónico] . Edition: -. Author: Lo, Y. M. Dennis. Publisher: Totowa, NJ : Humana Press Inc., 2006.  (Library)
  • Current protocols in molecular biology. Edition: -. Author: -. Publisher: [United States]: John Wiley and Sons, cop. 1998-  (Library)
  • Apoptosis, Cell Signaling, and Human Diseases [Recurso electrónico] : Molecular Mechanisms. Edition: -. Author: Srivastava, Rakesh. Publisher: Totowa, NJ : Humana Press Inc., 2007.  (Library)
  • In situ detection of DNA damage: methods and protocols. Edition: -. Author: -. Publisher: Totowa: Humana Press, cop. 2002  (Library)
  • Flow Cytometry [Recurso electrónico] : Principles and Applications. Edition: -. Author: Macey, Marion G.. Publisher: Totowa, NJ : Humana Press Inc., 2007.  (Library)
  • Clinical Applications of PCR [Recurso electrónico] . Edition: -. Author: Lo, Y. M. Dennis. Publisher: Totowa, NJ : Humana Press Inc., 2006.  (Library)
  • Current protocols in molecular biology. Edition: -. Author: -. Publisher: [United States]: John Wiley and Sons, cop. 1998-  (Library)