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Syllabus 2018-19 - 76713001 - Molecular and Cellular Pathology (Patología molecular y celular)

Caption
  • Level 1: Tutorial support sessions, materials and exams in this language
  • Level 2: Tutorial support sessions, materials, exams and seminars in this language
  • Level 3: Tutorial support sessions, materials, exams, seminars and regular lectures in this language
DEGREE: Máster Univ. en Biotecnología y biomedicina
FACULTY: Centro de Estudios de Postgrado
ACADEMIC YEAR: 2018-19
COURSE: Molecular and Cellular Pathology
SYLLABUS
1. COURSE BASIC INFORMATION
NAME: Molecular and Cellular Pathology
CODE: 76713001 ACADEMIC YEAR: 2018-19
LANGUAGE: English LEVEL: 1
ECTS CREDITS: 3.0 YEAR: 1 SEMESTER: SC
2. LECTURER BASIC INFORMATION
NAME: SILES RIVAS, EVA
DEPARTMENT: U103 - BIOLOGÍA EXPERIMENTAL
FIELD OF STUDY: 060 - BIOQUÍMICA Y BIOLOGÍA MOLECULAR
OFFICE NO.: B3 - B3-364 E-MAIL: esiles@ujaen.es P: 953212705
WEBSITE: https://www.uja.es/investigacion-y-transferencia/grupos-de-investigacion/estres-celular-y-edad
ORCID: https://orcid.org/0000-0003-4192-7008
LANGUAGE: - LEVEL: 1
NAME: LUQUE VÁZQUEZ, FRANCISCO
DEPARTMENT: U103 - BIOLOGÍA EXPERIMENTAL
FIELD OF STUDY: 420 - GENÉTICA
OFFICE NO.: B3 - B3-346 E-MAIL: fjluque@ujaen.es P: 953212527
WEBSITE: http://www.ujaen.es/investiga/cvi258/
ORCID: https://orcid.org/0000-0003-1354-3533
LANGUAGE: - LEVEL: 1
NAME: PERÁN QUESADA, MACARENA
DEPARTMENT: U130 - CIENCIAS DE LA SALUD
FIELD OF STUDY: 027 - ANATOMÍA Y EMBRIOLOGÍA HUMANA
OFFICE NO.: B3 - 212 E-MAIL: mperan@ujaen.es P: 953 21 365
WEBSITE: -
ORCID: https://orcid.org/0000-0001-7562-2347
LANGUAGE: - LEVEL: 1
3. CONTENT DESCRIPTION

Theoric curriculum

1. An introduction to molecular biology and applications to human disease

2. Molecular pathology of human disease.

    -Molecular basis of cancer: The hallmarks of cancer. Oncogenes and tumor supressor genes.   

    -Hypoxia: The role of reactive oxygen and nitrogen species in hypoxia. Hypoxia-inducible factor.

3. Molecular diagnosis of human disease and personalized medicine.

    -Molecular markers.

    -Radio and chemosensitivity.

4. Gene therapy.

    -Concept and types.

    -Vectors for gene transfer in gene therapy.

    -Main diseases target of gene therapy treatment

    -Therapeutic application of IPS cells

 

Laboratory practice

Effect of hypoxia on reactive oxygen species production

 

 

4. COURSE DESCRIPTION AND TEACHING METHODOLOGY

Teaching metodology:

a) Theoretical sessions, lectures and seminars in Spanish (26 hours).

b) Laboratory practice (4 hours).

  Teaching metodology for patie students:

a) Tutorial sessions, proposal of activities and supply of printted material in English (in presence of professor or virtual), 1 hour per week

b) Lecture (Practice): explanation of laboratory practice and seminars in English, 5 hours

c) Homework: 4 hours per week

Students with special educational needs should contact the Student Attention Service (Servicio de Atención y Ayudas al Estudiante) in order to receive the appropriate academic support

5. ASSESSMENT METHODOLOGY

Assessment methodology:

1) Attendance and active participation in theoretical sessions and lectures: 30%

2) Knowledge and understanding of the theoretical contents: 20%  

3) Presentation and discussion of assigned research papers: 30%

4) Attendence to laboratory sessions and lab report: 20%

6. BOOKLIST
MAIN BOOKLIST:
  • Cell cycle deregulation in cancer. Edition: 1st ed.. Author: -. Publisher: New York : Springer, 2010.  (Library)
  • Concepts in genetic medicine . Edition: -. Author: -. Publisher: Hoboken, N.J. : Wiley-Liss, cop. 2008.  (Library)
  • On line research articles. Edition: -. Author: -
  • Cell cycle deregulation in cancer. Edition: 1st ed.. Author: -. Publisher: New York : Springer, 2010.  (Library)
  • Concepts in genetic medicine . Edition: -. Author: -. Publisher: Hoboken, N.J. : Wiley-Liss, cop. 2008.  (Library)
  • On line research articles. Edition: -. Author: -
  • Human molecular genetics. Edition: 4th ed.. Author: Strachan, T.. Publisher: New York : Garland Science Taylor & Francis Group, c2010.  (Library)
  • Human molecular genetics. Edition: 4th ed.. Author: Strachan, T.. Publisher: New York : Garland Science Taylor & Francis Group, c2010.  (Library)
ADDITIONAL BOOKLIST:
  • Lentiviral vector systems for gene transfer. Edition: -. Author: -. Publisher: Georgetown: Eurekah.com: Landes Bioscience &#59; New York: Kluwer Academic Plenum Pub., cop. 2003  (Library)