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Syllabus 2018-19 - 10213007 - Clinical Microbiology (Microbiología clínica)

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  • Level 1: Tutorial support sessions, materials and exams in this language
  • Level 2: Tutorial support sessions, materials, exams and seminars in this language
  • Level 3: Tutorial support sessions, materials, exams, seminars and regular lectures in this language
DEGREE: Grado en Biología
FACULTY: FACULTY OF EXPERIMENTAL SCIENCES

ACADEMIC YEAR: 2018-19
SYLLABUS
1. COURSE BASIC INFORMATION
NAME: Clinical Microbiology
CODE: 10213007 ACADEMIC YEAR: 2018-19
LANGUAGE: English LEVEL: 1
ECTS CREDITS: 6.0 YEAR: 4 SEMESTER: SC
 
2. LECTURER BASIC INFORMATION
NAME: ORTEGA MORENTE, ELENA
DEPARTMENT: U130 - CIENCIAS DE LA SALUD
FIELD OF STUDY: 630 - MICROBIOLOGÍA
OFFICE NO.: B3 - 257 E-MAIL: eortega@ujaen.es P: 953212004
WEBSITE: -
LANGUAGE: English LEVEL: 1
 
NAME: PÉREZ PULIDO, RUBÉN
DEPARTMENT: U130 - CIENCIAS DE LA SALUD
FIELD OF STUDY: 630 - MICROBIOLOGÍA
OFFICE NO.: B3 - 214 E-MAIL: rppulido@ujaen.es P: 953213378
WEBSITE: http://www10.ujaen.es/conocenos/departamentos/ciesal/3871
LANGUAGE: English LEVEL: 1
 
3. CONTENT DESCRIPTION

THEORY:

LESSON 1. INTRODUCTION TO CLINICAL MICROBIOLOGY

-          Human pathogens: main characteristics of: viruses, prions, bacteria, fungi, protozoa, helminths

-          General mechanisms of pathogenesis

-          Immune response

-          Clinical syndromes

LESSON 2. INTRODUCTION TO VIROLOGY

-          Mechanisms of viral pathogenesis

-          Stages of viral diseases

-          Viral pathogenesis: lytic infections, latent infections, transforming infections (oncogenic viruses)

-          Immune response against viral infections

-          Viral escape from immune response

-          Antiviral agents

-          Viral diagnosis

LESSON 3. RNA VIRUSES

-          Nonenveloped positive-sense ssRNA viruses  

               Fam. Picornaviridae

               Fam. Caliciviridae

-          Enveloped positive-sense ssRNA viruses 

               Fam. Togaviridae

               Fam. Flaviridae

               Fam. Coronaviridae

               Fam. Retroviridae

-          Enveloped negative-sense ssRNA viruses 

               Fam. Rhabdoviridae

               Fam. Filoviridae

               Fam. Paramyxoviridae

               Fam. Orthomyxoviridae

-          Ambisense RNA viruses

               Fam. Bunyaviridae

               Fam. Arenaviridae

-          Nonenveloped  dsRNA viruses

               Fam. Reoviridae

LESSON 4. DNA VIRUSES

Nonenveloped ssDNA viruses

                               Fam. Parvoviridae

Nonenveloped dsDNA viruses

                               Fam. Papovaviridae

                               Fam. Adenoviridae

Enveloped dsDNA viruses

                               Fam. Herpesviridae

                               Fam. Poxviridae

                               Fam. Hepadnaviridae

Non-classified viruses

                               Hepatitis D virus

                               Hepatitis E virus

LESSON 5. RETROVIRUSES

-          Fam. Retroviridae (HIV virus)

-          Fam. Hepadnaviridae (Hepatitis B virus)

LESSON 6. PRIONS

-           Transmissible spongiform encephalopathies

LESSON 7. INTRODUCTION TO BACTERIOLOGY

-          Bacterial pathogenesis

-          Bacterial virulence factors

-          Immune response against bacterial infections

-          Bacterial escape from immune response

-          Antibacterial agents

-          Bacterial diagnosis

LESSON 8. GRAM-POSITIVE AND GRAM-NEGATIVE COCCI

-          Staphylococcus and related Gram-positive cocci ( S. aureus, S. epidermidis and other coagulase-negative cocci),

-          Streptococcus (S. pyogenes, S. agalactiae, S. pneumoniae)

-          Enterococcus and related cocci

-          Anaerobic Gram-positive cocci

-          Gram-negative cocci (Fam. Neisseriaceae)

LESSON 9. GRAM-POSITIVE RODS

-          Bacillus

-          Clostridium

-          Listeria and Erysipelothrix

-          Corynebacterium and related rods

-          Nocardia and related bacteria

-          Mycobacterium

-          Anaerobic Gram-positive rods ( Actinomyces, Propionibacterium, Mobiluncus, Lactobacillus, Bifidobacterium and Eubacterium)

LESSON 10. GRAM-NEGATIVE RODS

-          Fam. Enterobacteriaceae

-          Vibrio and Aeromonas

-          Campylobacter and Helicobacter

-          Pseudomonas and related bacteria

-          Haemophilus and related bacteria

-          Bordetella, Francisella and Brucella

-          Legionella

-          Anaerobic Gram-negative rods ( Bacteroides)

LESSON 11. SPIROCHAETALES, MYCOPLASMAS AND OBLIGATE INTRACELLULAR BACTERIA

-          Spirochaetales: Treponema, Borrelia, Leptospira

-          Mycoplasmas

-          Familia Rickettsiaceae

-          Chlamydia and Chlamydophila

LESSON 12. INTRODUCTION TO MYCOLOGY

-          Fungal pathogenesis: primary and opportunistic pathogens: virulence factors and pathogenic potential

-          Fungal diagnosis

-          Antifungal agents

LESSON 13. FUNGAL INFECTIONS

-          Superficial mycoses

-          Cutaneous mycoses

-          Subcutaneous mycoses

-          Systemic mycoses

-          Opportunistic mycoses

-          Mycotoxins

SEMINAR: MICROBIOLOGICAL DIAGNOSIS

-          Sample collection from: blood, sterile liquids, airways, eyes and ears, lesions, tissues, urine, feces and genital tract.

-          Detection and identification of pathogens: Microscopy, detection of antigens, detection of nucleic acids, culture and serology.

-          Susceptibility to antimicrobials: agar diffusion test and broth micro-dilution method

LABORATORY CLASSES:

- General and specific culture media

- Isolation and identification of human pathogens from urine and respiratory tract

- Resistance of bacteria to antimicrobials

- Guided visit to the Microbiology Unit of Hospital "Ciudad de Jaén". 

4. COURSE DESCRIPTION AND TEACHING METHODOLOGY

- Lecture (Theory): Tutorial session, proposal and correction of activities and exercises in English (in presence of professor or virtual): 1 hour per week.

- Lecture (Practice): Tutorial session, supply of press material (in presence of professor or virtual): 1 hour per week.

- Homework: 4 hours per week.

Attendance to laboratory classes is mandatory. Voluntary activities are also proposed in the Virtual Platform of University of Jaén.

Tutorial support sessions, materials and exams in English. For regular spanish students the default teaching language will be Spanish. Exchange international students can electively join regular courses in Spanish whenever they wish.

Students with special educational needs should contact the Student Attention Service (Servicio de Atención y Ayudas al Estudiante) in order to receive the appropriate academic support

5. ASSESSMENT METHODOLOGY

Theory will be evaluated with a written exam and a term paper. Attendance to laboratory classes is mandatory. Voluntary activities are also proposed in the Virtual Platform of University of Jaén.

6. BOOKLIST
MAIN BOOKLIST:
  • Brock Biology of Microorganisms. Edition: 12th ed.. Author: -. Publisher: San Francisco, CA : Pearson Benjamin Cummings, c2009.  (Library)
  • Manual of clinical microbiology. Edition: 10th ed. Author: -. Publisher: Washington, DC : ASM Press, c2011  (Library)
  • Medical microbiology. Edition: 7th ed. Author: Murray, Patrick R. Publisher: Philadelphia : Mosby Elsevier, cop. 2013  (Library)