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Syllabus 2015-16 - 72512008 - Molecular and Cellular Pathology (Patología molecular y celular)

Caption
  • Level 1: Tutorial support sessions, materials and exams in this language
  • Level 2: Tutorial support sessions, materials, exams and seminars in this language
  • Level 3: Tutorial support sessions, materials, exams, seminars and regular lectures in this language
DEGREE: Máster en Biotecnología y biomedicina
FACULTY: Centro de Estudios de Postgrado
ACADEMIC YEAR: 2015-16
COURSE: Molecular and Cellular Pathology
SYLLABUS
1. COURSE BASIC INFORMATION
NAME: Molecular and Cellular Pathology
CODE: 72512008 ACADEMIC YEAR: 2015-16
LANGUAGE: English LEVEL: 1
ECTS CREDITS: 4.0 YEAR: 1 SEMESTER: AN
2. LECTURER BASIC INFORMATION
NAME: SILES RIVAS, EVA
DEPARTMENT: U103 - BIOLOGÍA EXPERIMENTAL
FIELD OF STUDY: 060 - BIOQUÍMICA Y BIOLOGÍA MOLECULAR
OFFICE NO.: B3 - B3-364 E-MAIL: esiles@ujaen.es P: 953212705
WEBSITE: https://www.uja.es/investigacion-y-transferencia/grupos-de-investigacion/estres-celular-y-edad
ORCID: https://orcid.org/0000-0003-4192-7008
LANGUAGE: English LEVEL: 1
NAME: LUQUE VÁZQUEZ, FRANCISCO
DEPARTMENT: U103 - BIOLOGÍA EXPERIMENTAL
FIELD OF STUDY: 420 - GENÉTICA
OFFICE NO.: B3 - B3-346 E-MAIL: fjluque@ujaen.es P: 953212527
WEBSITE: http://www.ujaen.es/investiga/cvi258/
ORCID: https://orcid.org/0000-0003-1354-3533
LANGUAGE: English LEVEL: 1
NAME: PERÁN QUESADA, MACARENA
DEPARTMENT: U130 - CIENCIAS DE LA SALUD
FIELD OF STUDY: 027 - ANATOMÍA Y EMBRIOLOGÍA HUMANA
OFFICE NO.: B3 - 212 E-MAIL: mperan@ujaen.es P: 953 21 365
WEBSITE: -
ORCID: https://orcid.org/0000-0001-7562-2347
LANGUAGE: English LEVEL: 1
3. CONTENT DESCRIPTION

Theoric curriculum

1. An introduction to molecular biology and applications to human disease

 2. Molecular pathology of human disease.

-Molecular basis of cancer: The hallmarks of cancer. Oncogenes and tumor supressor genes. Angiogenesis. Cell death. Inflammation and cancer.

-Hypoxia: The role of reactive oxygen and nitrogen species in hypoxia. Hypoxia-inducible factor.

-Molecular basis of muscular dystrophies and HIV-1 infection.

3. Molecular diagnosis of human disease and personalized medicine.

-Molecular markers.

-Radio and chemosensitivity.

4. Gene therapy.

-Concept and types.

-Vectors for gene transfer in gene therapy.

-Main diseases target of gene therapy treatment with special attention to cancer, monogenic disorders as muscular dystrophies and HIV-1 infection.

-Therapeutic application of IPS cells

Laboratory practice

Effect of hypoxia on reactive oxygen species production

 

4. COURSE DESCRIPTION AND TEACHING METHODOLOGY

 Teaching metodology:

a) Academic sessions to the great group (20 hours).

b) Academic sessions to the small group of students: seminars, laboratory practice (15 hours).

c) Collective tutorial sessions (5 hours)

 

Course description and teaching methodology for patie students:

Lecture (Theory):

1

 

Hours per week

 

Lecture (Practice):

 

4

 

Hours

 

Seminars

 

1

 

Hour

 

Homework

 

4

 

Hours per week

 

Students with special educational needs should contact the Student Attention Service (Servicio de Atención y Ayudas al Estudiante) in order to receive the appropriate academic support

5. ASSESSMENT METHODOLOGY

Assessment methodology:

1) Attendance and active participation in theoretical sessions and lectures: 40%

2) Presentation and discussion of assigned research papers: 40%

3) Attendence to laboratory sessions and lab report: 20%

 

6. BOOKLIST
MAIN BOOKLIST:
  • Cell cycle deregulation in cancer. Edition: 1st ed.. Author: -. Publisher: New York : Springer, 2010..
    • Notes: Bloque II
     (Library)
  • Cell death. Edition: -. Author: -. Publisher: Chichester, West Sussex ; Hoboken, NJ : John Wiley & Sons, c2010..
    • Notes: Bloque II
     (Library)
  • Concepts in genetic medicine. Edition: -. Author: -. Publisher: Hoboken, N.J. : Wiley-Liss, cop. 2008..
    • Notes: Bloque IV
     (Library)
  • Different scientific articles. Edition: -. Author: -
ADDITIONAL BOOKLIST:
  • Cancer Epigenetics. Edition: 1ª. Author: Tollefsbol T. Publisher: CRC Press  (Library)
  • Lentiviral vector systems for gene transfer. Edition: -. Author: -. Publisher: Georgetown: Eurekah.com: Landes Bioscience &#59; New York: Kluwer Academic Plenum Pub., cop. 2003  (Library)